This study examines the impact of an information system on user attitudes and perceptions of job characteristics. These impacts were assessed with a quasi-experimental research design for a sample of nurses in a major urban hospital. After testing for and rejecting possible confounding influences of the pretest scores, comparisons were made between pre-implementation and post-implementation attitudes and perceptions. Results showed little change in job perceptions and no significant change in attitudes toward the system. The importance of these findings is discussed within the context of alternative models for explaining the organizational impacts of information systems.